Next Exit follows a research scientist who makes headlines proving she can track people after death, and her radical scientific study is looking for volunteers for a pain-free passing to the afterlife. Rose sees a way out and Teddy sees his chance to finally make it. When fate has the two strangers sharing a car rental, they set out on a lengthy road trip to the unknown. As these two misfits quarrel their way across the country, their friction gradually gives way to a deep connection that they’ve both needed.